Common food
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Similac Advance powder, when mixed with tap water, creates a smooth, creamy, off-white liquid with a mild, slightly sweet, milky taste designed to mimic breast milk. It's a nutritionally complete infant formula engineered to support early brain and eye development. The powder itself is fine and free-flowing, dissolving easily without clumping.
Calorie split: 8% protein · 42% carbs · 50% fat
↓ Full nutritionParents trust it for its consistent nutritional profile and the peace of mind it offers as a reliable breast milk substitute or supplement. Its familiar, gentle taste is often well-accepted by infants transitioning from breastfeeding.
As a processed powder, it lacks some of the dynamic antibodies and live cells found in fresh breast milk. Some infants may experience constipation or fussiness, and it is not suitable for infants with cow's milk protein allergy. Always consult a pediatrician before use and follow preparation instructions precisely to avoid nutrient dilution or concentration.
The 'Advance' formula was one of the first to include the specific fatty acids DHA and ARA, sourced from oil, to more closely match the composition of human breast milk.
| Water | 87.6 g |
| Energy | 66.0 kcal |
| Protein | 1.4 g |
| Total lipid (fat) | 3.6 g |
| Carbohydrate, by difference | 6.9 g |
| Fiber, total dietary | 0.00 g |
| Total Sugars | 6.9 g |
| Calcium, Ca | 54.0 mg |
| Iron, Fe | 1.2 mg |
| Magnesium, Mg | 5.0 mg |
| Phosphorus, P | 28.0 mg |
| Potassium, K | 69.0 mg |
| Sodium, Na | 19.0 mg |
| Zinc, Zn | 0.50 mg |
| Copper, Cu | 0.07 mg |
| Selenium, Se | 1.5 ug |
| Vitamin C, total ascorbic acid | 5.9 mg |
| Thiamin | 0.07 mg |
| Riboflavin | 0.10 mg |
| Niacin | 0.69 mg |
| Vitamin B-6 | 0.04 mg |
| Folate, total | 10.0 ug |
| Folic acid | 10.0 ug |
| Folate, food | 0.00 ug |
| Folate, DFE | 17.0 ug |
| Choline, total | 15.1 mg |
| Vitamin B-12 | 0.17 ug |
| Vitamin B-12, added | 0.17 ug |
| Vitamin A, RAE | 59.0 ug |
| Retinol | 59.0 ug |
| Carotene, beta | 0.00 ug |
| Carotene, alpha | 0.00 ug |
| Cryptoxanthin, beta | 0.00 ug |
| Lycopene | 0.00 ug |
| Lutein + zeaxanthin | 0.00 ug |
| Vitamin E (alpha-tocopherol) | 0.66 mg |
| Vitamin E, added | 0.66 mg |
| Vitamin D (D2 + D3) | 1.0 ug |
| Vitamin K (phylloquinone) | 5.3 ug |
| Alcohol, ethyl | 0.00 g |
| Caffeine | 0.00 mg |
| Theobromine | 0.00 mg |
| Fatty acids, total saturated | 1.2 g |
| SFA 4:0 | 0.00 g |
| SFA 6:0 | 0.01 g |
| SFA 8:0 | 0.11 g |
| SFA 10:0 | 0.08 g |
| SFA 12:0 | 0.49 g |
| SFA 14:0 | 0.18 g |
| SFA 16:0 | 0.26 g |
| SFA 18:0 | 0.12 g |
| Fatty acids, total monounsaturated | 1.3 g |
| MUFA 16:1 | 0.00 g |
| MUFA 18:1 | 1.3 g |
| MUFA 20:1 | 0.01 g |
| MUFA 22:1 | 0.00 g |
| Fatty acids, total polyunsaturated | 0.80 g |
| PUFA 18:2 | 0.72 g |
| PUFA 18:3 | 0.08 g |
| PUFA 18:4 | 0.00 g |
| PUFA 20:4 | 0.02 g |
| PUFA 20:5 n-3 (EPA) | 0.00 g |
| PUFA 22:5 n-3 (DPA) | 0.00 g |
| PUFA 22:6 n-3 (DHA) | 0.01 g |
| Cholesterol | 2.0 mg |
Is it safe to mix with tap water?
Yes, in areas with safe, potable tap water. However, for infants under 3 months, immunocompromised infants, or in areas with water quality concerns, using cooled boiled water or distilled water is recommended to eliminate any risk of pathogens.
How does the powder differ from ready-to-feed liquid?
The powder is more economical and has a longer shelf life. The nutritional content is designed to be equivalent once properly mixed, but the ready-to-feed liquid offers ultimate convenience and sterility.
Can I use it after the 'use by' date?
No. The expiration date is critical for ensuring nutrient potency and safety. Discard any unused prepared formula after 24 hours in the refrigerator, and discard any opened powder after 30 days.
NRF9.3 index — Fulgoni, Keast & Drewnowski, 2009. Computed from USDA nutrients.
Composite of energy density (Rolls et al., 1999), protein & fiber satiety, minus sugar. A calculated heuristic — ranks satiety-per-calorie, not a clinical measure.
Sodium-to-potassium ratio: 0.28 (lower is better — aim for ≤ 1)
Sodium:potassium per WHO potassium guidance. Computed from USDA nutrients.