In a shallow dish, combine cooled coffee and coffee liqueur (if using). Set aside.
In a medium bowl, beat Greek yogurt, cream cheese, honey, and vanilla until smooth and creamy.
Briefly dip each ladyfinger into the coffee mixture (about 2 seconds per side) and arrange a layer in the bottom of a 8x8-inch dish or 6 individual serving glasses.
Spread half of the yogurt mixture over the ladyfingers.
Repeat with another layer of dipped ladyfingers and remaining yogurt mixture.
Dust the top with cocoa powder using a fine-mesh sieve.
Cover and refrigerate for at least 4 hours, preferably overnight, to allow flavors to meld.
Before serving, dust with additional cocoa powder if desired.
Tips
For a non-alcoholic version, omit the coffee liqueur.
Use decaf coffee if you prefer less caffeine.
Store leftovers in the refrigerator for up to 3 days.